Table 1.

Demographic patient data and optical coherence tomography parameters

Characteristics	ALS patients (N = 24)	Healthy controls (N = 24)
Diagnosis – no. (%)
Clinically definite	20 (83)	n.a.
Clinically probable	4 (17)	n.a.
Age – yr (range)	61.5 ± 13.0 (34–82)	61.6 ± 15 (33–84)
Male sex – no. (%)	19 (79)	17 (71)
Interval disease manifestation to OCT – mo (range)	22.3 ± 22.57 (3–120)	n.a.
Riluzole treatment at OCT – no. (%)	7 (29)	n.a.
Duration of riluzole treatment before OCT – mo (range)	17 (1–55)	n.a.
OCT parameters
Mean RNFL – µm	93.23 ± 10.67	99.98 ± 10.89
Mean GCIP – µm	66.15 ± 6.57	66.47 ± 6.62
Mean INL – µm	24.72 ± 3.22	27.87 ± 4.34
Mean OPL – µm	29.50 ± 3.58	30.89 ± 4.47
Mean ONL – µm	61.57 ± 7.53	60.50 ± 7.82
P.E. GCIP – µm	97.13 ± 8.83	99.98 ± 9.21
P.E. INL – µm	37.42 ± 4.64	43.29 ± 4.22
P.E. OPL – µm	41.25 ± 5.98	35.52 ± 7.00
P.E. ONL – µm	107.67 ± 10.61	105.91 ± 12.68
MT – µm	309.83 ± 17.29	318.24 ± 15.65

Table 1 Indicated are the demographic data and the mean retinal layer thicknesses and standard deviations for the acquired parameters of ALS patients and healthy controls. The abbreviations are as follows: ALS, amyotrophic lateral sclerosis; GCIP, ganglion cell/inner plexiform layer complex; INL, inner nuclear layer; Mean, mean layer thickness; MT, macular thickness; n.a., not applicable; OCT, optical coherence tomography; ONL, outer nuclear layer; OPL, outer plexiform layer; P.E., point estimate measurement; RNFL, retinal nerve fiber layer.