Table I.
Genes co-regulated by STZ and Rosi.
| Gene name | STZ log2 (FC)a | Rosi log2 (FC)b | Functionc |
|---|---|---|---|
| Marcks | −1.238 | 1.154 | Marcks is the most prominent cellular substrate for protein kinase C (PKC); binds to calmodulin, actin and synapsin; inhibits F-actin cross-linking activity |
| Glipr2 | −1.373 | 1.075 | Unannotated |
| Cep170 | −1.139 | 1.005 | Plays a role in microtubule organization |
a
Log2 value of corresponding genes from mice with STZ-induced diabetes compared with the control (untreated) samples
b
corresponding genes from mice with STZ-induced diabetes treated with Rosi compared with untreated mice with STZ-induced diabetes
c
UniProtKB annotation function of the corresponding genes. FC, fold change; STZ, streptozotocin; Rosi, rosiglitazone.