Table 3.
Summary of the SNPs/variants detected in the LATS1 of the urinary bladder cancerous tissues.
| Samples | No. of SNPs/variants within the LATS1 gene of this sample | Position of SNP/variant | LATS1 expression |
|---|---|---|---|
| UC2, UC3, UC6, UC22, UC25 | No SNPs | U6 showed + LATS1 expression. | |
| UC19 | 1 SNP | 16045 | NA |
| UC14 | 1 SNP | 35366 | + |
| UC18 | 1 variant | 41625 | NA** |
| UC7 | 1 SNP | 41736 | +* |
| UC10 | 2 SNPs/variants | 41736 + 42029 | NA |
| UC17 | 2 SNPs/variants | 41625 + 41736 | NA |
| UC20 | 3 SNPs | 16045 + 35366 + 41736 | + |
| UC16 | 3 SNPs/variants | 34614 + 41625 + 41736 | NA |
| UC24 | 3 SNPs/variants | 41625 + 41736 + 42029 | NA |
| UC13 | 4 SNPs/variants | 16045 + 35366 + 41736 + 42029 | +++ |
| UC11 | 4 SNPs | 16045 + 34614 + 41736 + 56177 | −*** |
| UC4 | 4 SNPs/variants | 34614 + 35366 + 41625 + 41736 | + |
| UC5 | 4 SNPS/variants | 34614 + 41625 + 41736 + 42029 | + |
| UC12 | 4 SNPs/variants | 35366 + 41625 + 41736 + 42029 | NA |
| UC9 | 5 SNPs/variants | 16045 + 34614 + 41625 + 41736 + 56177 | NA |
| UC21 | 5 SNPs/variants | 34614 + 35366 + 41736 + 42029 + 56177 | NA |
| UC8 | 5 SNPs/variants | 35366 + 41625 + 41736 + 42029 + 56177 | ± |
| UC1 | 6 SNPs/variants | 16045 + 34614 + 35366 + 41625 + 41736 + 56177 | − |
| UC15 | 6 SNPs/variants | 16045 + 34614 + 35366 + 41736 + 42029 + 56177 | − |
| UC23 | 7 SNPs/variants | 16045 + 34614 + 35366 + 41625 + 41736 + 42029 + 56177 | NA |
*
+, Showed LATS1 mRNA expression.
**
NA, Not Available.
***
−, Did not show LATS1 mRNA expression.
The bold font indicates the position of four SNPs, when combined, were associated with eliminated steady state levels of LATS1 RNA.