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. Author manuscript; available in PMC: 2015 Jan 13.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2013 Apr 25;40(4):437–449. doi: 10.1007/s10928-013-9317-1

Fig. 2.

Fig. 2

Schematic representation of a physiologically-based pharmacokinetic (PBPK) model of docetaxel incorporating intravenous drug administration, intestinal and hepatic metabolism, enterohepatic recycling (EHR), glomerular filtration, tubular reabsorption, urinary and fecal elimination and ABCB1 transport