. Author manuscript; available in PMC: 2015 Mar 2.

Published in final edited form as: Obstet Gynecol. 2013 Jun;121(6):1263–1271. doi: 10.1097/AOG.0b013e31829006d9

Table 2.

Association Between Infertility and Miscarriage for Fresh, Nondonor InVitro Fertilization Cycles Resulting in Pregnancy, 2000–2010

Outcome	Tubal Factor^†^‡	Male Factor^†^‡	Bivariate Analysis		Multivariable Analysis^*
Outcome	Tubal Factor^†^‡	Male Factor^†^‡	RR (95% CI)	P	Adjusted RR (95% CI)	P
Any miscarriage (less than 20 wk of gestation)	5,491 (13.99)	9,785 (12.65)	1.11 (1.07–1.14)	<.001	1.08 (1.04–1.12)	.001
Early miscarriage (less than 15 wk of gestation)	4,989 (12.87)	9,163 (11.94)	1.08 (1.04–1.11)	<.001
Late miscarriage (15–20 wk of gestation)	502 (1.47)	622 (0.91)	1.61 (1.43–1.81)	<.001

RR, relative risk; CI, confidence interval. Data are n (%) unless otherwise specified.

Controlled for maternal age, number of prior spontaneous miscarriages, number of prior preterm births, number of prior full-term births, number of prior assisted reproductive technology cycles, use of intracytoplasmic sperm injection, use of assisted hatching, the embryo stage at transfer, the number of embryos transferred, the number of supernumerary embryos cryopreserved, the number of oocytes retrieved, and year.

^†

The number of cycles with no miscarriage was 33,762 among the tubal factor group and 67,558 among the male factor group.

^‡

Percent any miscarriage=100×number any miscarriage/(number any miscarriage+number no miscarriage); percent early miscarriage=100×number early miscarriage/(number early miscarriage+number no miscarriage); percent late miscarriage=100×number late miscarriage/(number late miscarriage+number no miscarriage).