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. Author manuscript; available in PMC: 2015 Jan 13.
Published in final edited form as: Dig Dis Sci. 2010 Jul 20;56(2):397–405. doi: 10.1007/s10620-010-1314-2

Table 1.

Genomic amino acid sequences for primates in the Pro-Glu-Leu-Pro-Lys (PELPK) region of the carcinoembryonic antigen (CEA) gene

Primates Sequences
HCEA-A1 PELPKPSISSNNSKPVEDKDAVAFTCEPETQDA
Common Chimpanzee (old world) PELPKPFIFSINFKPVEDKDAGAFTCEPETQDA
Rhesus Macaque (old world) PELPKPSISSNNSKPVEDKDAGAFTCEPETQDA
Tarsier (new world) PELPKPSISSNNSKPVEDKDAVAFTCEPETQDA
Mangaby (old world) RELPKPFIFSFNFKPVEDKDAGAFTCEPETQDA
Red Howler (new world) RELPKPSIFSFNSKPVEDKDAGAFTCEPETQDA
Black Howler (new world) RELPKPSIFSFNSKPVEDKDAGAFTCEPETQDA
Squirrel (new world) RELPKPSIFSFNSKPVEDKDAGAFTCEPETQDA
Titi (new world) PELPKPSIFSFNSKPVEDKDAGAFTCEPETQDA
Common Marmoset (new world) PELPKPSISSINSKPVEDKDAGAFTCEPETQDA
Cotton Top Tamarin (new world) PELPKPSISSNNSKPVEDKDAGAFTCEPETQDA

Genomic DNA from blood samples of Old- and New World primates are compared. HCEA-A1 is the normal human sequence derived from a human colorectal cancer cell line (MIP-101). Changes from the human sequences in the primates are shown in bold