Table 1.
Non-ECM Proteins
| Gene Name |
MW. | ID. Count | Avg. Sequence Coverage |
Avg. Unique Peptides |
Norm. Spectral Intensity |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rank | Accession | Protein name | (kDa) | N | I | IIb | N | I | IIb | N | I | IIb | I/N | IIb/I | |
| 238 | IPI00231949 | CD14 | Monocyte diff. antigen CD14 | 40 | 4 | 4 | 4 | 13% | 22% | 16% | 3 | 6 | 5 | 3.46 * | 1.08 |
| 478 | IPI00369645^ | CD68 | Cd68 | 35 | 0 | 4 | 4 | - | 5% | 6% | - | 2 | 2 | Up ** | 2.05 |
| 342 | IPI00207828^ | LBP | LPS-binding protein | 54 | 0 | 4 | 4 | - | 10% | 10% | - | 4 | 4 | Up ** | 1.08 |
| 880 | IPI00208224^ | STAT3 | STAT3 | 88 | 0 | 3 | 2 | - | 2% | 3% | - | 1 | 2 | Up | 2.40 |
| 182 | IPI00212811^ | CTSB | Cathepsin B | 37 | 1 | 4 | 4 | 17% | 14% | 11% | 1 | 5 | 5 | 2.96 | 0.64 |
| 82 | IPI00212731^ | CTSD | Cathepsin D | 45 | 4 | 4 | 4 | 16% | 25% | 31% | 3 | 9 | 10 | 27.27 *** | 0.97 |
| 526 | IPI00207663 | CTSZ | Cathepsin Z | 34 | 0 | 4 | 4 | - | 8% | 6% | - | 2 | 2 | Up *** | 0.66 * |
| 614 | IPI00324585 | ITGA1 | Integrin alpha-1 | 131 | 2 | 4 | 2 | 1% | 1% | 1% | 1 | 3 | 2 | 6.09 * | 0.19 |
| 564 | IPI00372689^ | ITGA3 | Integrin alpha-3 | 117 | 1 | 4 | 3 | 3% | 3% | 2% | 2 | 3 | 2 | 4.31 ** | 0.58 |
| 204 | IPI00205166 | ITGA6 | Integrin alpha-6 | 119 | 4 | 4 | 4 | 3% | 6% | 7% | 3 | 6 | 8 | 4.02 ** | 1.08 |
| 169 | IPI00191681 | ITGB1 | Integrin beta-1 | 88 | 4 | 4 | 4 | 5% | 8% | 8% | 4 | 7 | 7 | 2.82 *** | 1.02 |
| 568 | IPI00199853 | ITGAM | Integrin beta 2 alpha subunit | 127 | 0 | 4 | 4 | - | 2% | 2% | - | 2 | 2 | Up | 3.85 |
| 235 | IPI00214435^ | ITGB4 | Integrin beta-4 | 201 | 4 | 4 | 4 | 2% | 2% | 2% | 4 | 6 | 5 | 0.78 | 0.82 |
| 396 | IPI00201586^ | HSPB1 | Heat shock protein beta-1 | 23 | 4 | 4 | 4 | 7% | 16% | 14% | 1 | 3 | 3 | 1.54 | 0.73 |
| 78 | IPI00339148 | HSPD1 | Heat shock 60 kDa protein | 61 | 4 | 4 | 4 | 19% | 32% | 28% | 9 | 15 | 13 | 3.31 * | 1.14 |
| 820 | IPI00196751 | HSPA1 | Heat shock 70 kDa protein | 70 | 2 | 2 | 0 | 2% | 6% | - | 3 | 2 | - | 3.30 | Down |
^
()peptides match to additional IPI entries (same protein group)
*
() P < 0.05
**
() P < 0.01
***
() P < 0.001
ID Count=number of runs, out of the four experiments, in which a protein was identified. Norm. Spectral Intensity=summed intensity of MS/MS product ions for all spectra mapped to a given protein normalized by molecular weight.