Figure 2.
Insulin resistance in adolescents with obesity and T2D. Insulin sensitivity in mg/kg/min as determined by hyperinsulinemic-euglycemic clamp in adolescents (aged 12–19 years): normal weight/control (n = 12), obese (n = 13), and those with T2D (n = 14). All three groups were similar in age, pubertal stage, and activity level; the obese and T2D groups were similar in BMI. *P <0.001 versus control. ‡P <0.02 versus obese.26 Abbreviation: T2D, type 2 diabetes mellitus.