Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Signalling through κ opioid receptors (KOPr) induced by dynorphin or TRK820 regulates VEGF signalling, especially VEGFR2 expression, by activating the cAMP/PKA pathway in ECs. The balance between the expression of activators and inhibitors of angiogenesis controls angiogenesis in development and in tumours (adapted from Yamamizu et al., 2011).
