Figure 6.

Bias factors heavily depend on the standard chosen for normalization. Transduction coefficients generated in Figure 5C were normalized to DPDPE (as before), SNC-80 or UFP-512 as indicated. Note the difference in the bias profile of SNC-80 when either DPDPE or UFP-512 was used as the standard. Also note that internalization versus cyclase bias displayed by SNC-80 when DPDPE was the standard is of same magnitude but opposite as the bias displayed by DPDPE when SNC-80 was the standard.