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. 2014 Dec 28;12:129. doi: 10.1186/1477-7827-12-129

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© Leguy et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Microscopic analysis of placental villi in normal pregnancy and pregnancy complicated by aneuploidy. After termination of pregnancy, 55 aneuploid placentae were analysed by experimented pathologists at the macroscopic level, and the histological level after being fixed in formalin, included in paraffin and stained with hematein-eosin-saffron. Mature villi i.e. small diameter, strong staining, presence of fetal vessels, decreased connective tissue, covered by trophoblastic tissue. Immature hydropic villi i.e. large diameter, pale staining, few fetal vessels, connective tissue, decreased trophoblastic tissue.