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Principal macroscopic and microscopic findings regarding placentas complicated by aneuploidy
| Trisomy 21 (n = 31) | Trisomy 18 (n = 21) | Trisomy 13 (n = 3) | |
|---|---|---|---|
| Macroscopy | |||
| Hypotrophy | 16 | 12 | 0 |
| Immaturity | 24 | 14 | 0 |
| Sponginess | 20 | 10 | 0 |
| Hydropsy | 24 | 20 | 0 |
| Single umbilical artery | 0 | 4 | 0 |
| Histology | |||
| Hydropic villi | 28 | 19 | 2 |
| Immature villi | 20 | 6 | 0 |
| Post-mature villi | 12 | 6 | 0 |
| Calcifications | 4 | 4 | 2 |
| Fibrin deposits | 12 | 4 | 0 |
| Trophoblastic cysts | 0 | 4 | 0 |
| Bullous dystrophy | 8 | 0 | 0 |
