Figure 1.
Varenicline did not affect the expression of an ethanol-induced CPP. Shown are mean ± SEM sec/min spent on the grid floor during a 30-min preference test after varenicline (0, 1 or 1.5 mg/kg) and then saline treatment, given 15 min later. VAR x = varenicline tartrate dose in mg/kg; G+ = ethanol paired with grid floor; G- = ethanol paired with hole floor. ***: p<0.001 for the main effect of floor type (G+, G−), indicating that ethanol induced a significant CPP.