Table 2. Effects of alcohol, sex and interaction of [11C]SCH 23390 binding potential.
| Alcohol | Sex | Alcohol × Sex | ||||
|---|---|---|---|---|---|---|
| Region of Interest | F (1,30) | p | F (1,30) | p | F (1,30) | p |
| Prefrontal Cortex | 2.43 | 0.13 | 1.59 | 0.22 | 7.24 | 0.012* |
| Lateral PFC | 1.7 | 0.203 | 3.09 | 0.09+ | 7.53 | 0.01* |
| Ventrolateral PFC | 1.77 | 0.193 | 5.14 | 0.031* | 7.11 | 0.012* |
| Dorsolateral PFC | 1.57 | 0.221 | 1.8 | 0.19 | 7.5 | 0.01* |
| Medial | 3.19 | 0.084+ | 0.81 | 0.37 | 6.8 | 0.014* |
| Frontopolar | 2.04 | 0.163 | 2.93 | 0.097+ | 4.37 | 0.045* |
| Orbitofrontal | 1.34 | 0.256 | 0.08+ | 0.784 | 4.66 | 0.039* |
| Striatum | 1.12 | 0.3 | 0.91 | 0.35 | 3.48 | 0.072+ |
| Caudate | 1.92 | 0.176 | 0.41 | 0.53 | 3.12 | 0.088+ |
| Putamen | 0.54 | 0.468 | 1.51 | 0.23 | 3.54 | 0.07+ |
| Nucleus accumbens | 4.47 | 0.043* | 0.57 | 0.46 | 3.81 | 0.0603+ |
| SN/VTA | 3.78 | 0.0614+ | 3.12 | 0.088+ | 1.38 | 0.249 |
ROI's are hierarchically structured. F's and p's are from 2(alcohol) × 2(prenatal stress) × 2(sex) ANOVA's. SN/VTA=substantia nigra/ventral tegmental area.
*
p<0.05
+
p<0.10