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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Alcohol Clin Exp Res. 2014 Dec;38(12):3017–3023. doi: 10.1111/acer.12578

Figure 1.

Figure 1

Comparison of topiramate and placebo across study periods in the full sample (n=138). Values are means (SEM).

A: Mean percent heavy drinking days (PHDD). There was a significant interaction of medication group by study period (p=0.03) on PHDD.

B: Mean natural log γ-glutamyltranspeptidase (GGTP) concentration. The interaction of medication group by study period was not significant for GGTP (p=0.18).

C: Mean Short Index of Problems (SIP) score. There was significant main effect of medication group (p=0.001) on SIP score, but no interaction of medication group by study period.