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Distal S1P1/3 stimulation promotes sprout formation in arterial and venular endothelial cells. (A) Schematic of distal S1PR agonist stimulation in the absence of VEGF. (B) Sprout density of HAAECs and HUVECs under distal agonist stimulation, normalized to basal media. (C) Representative images of (B). Magnification=20×. Green color indicates green fluorescent protein (GFP). Error bars represent standard error. *p<0.05. Color images available online at www.liebertpub.com/tea
