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Continuous co-treatment with ZnPy enhances F10 cytotoxicity only under limited conditions. (A,B) Plots of cell viability for (A) PC3 and (B) C4-2 cells co-treated with F10 and ZnPy under the conditions indicated. (C,D) Plots of caspase 3/7 activity for (C) PC3 and (D) C4-2 cells under the conditions indicated. Cytotoxicity is independent of F10 concentration for ZnPy concentrations >150 nM for PC3 and > 300 nM for C4-2 cells.
