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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Am J Reprod Immunol. 2014 Aug 28;73(2):162–174. doi: 10.1111/aji.12313

Table 3.

The odds ratio (OR) (95% confidence interval) of a top-quartile concentration of the protein listed on the left on days 1, 7 and 14 with the newborn’s mother having acknowledged both a UTI (urinary tract infection) and CVI (cervicovaginal infection), A UTI without CVI, or a CVI without UTI. The referent group consists of all newborns whose mothers did not have either infection (day 1, N=621, day 7, N=631, day 14, N=574). All ORs are adjusted for gestational age category, Black race, and public insurance. Significantly elevated OR are bolded and shaded while significantly reduced OR are bolded, italicized, and shaded.

Protein in top quartile Both UTI and CVI UTI no CVI CVI no UTI

Day 1 Day 7 Day 14 Day 1 Day 7 Day 14 Day 1 Day 7 Day 14
CRP 1.1 (0.4, 2.6) 0.9 (0.4, 2.2) 0.7 (0.2, 3.0) 0.7 (0.4, 1.2) 1.2 (0.7, 1.9) 1.2 (0.7, 2.0) 1.7 (1.1, 2.8) 1.1 (0.6, 1.8) 0.8 (0.5, 1.5)
SAA 1.0 (0.4, 2.5) 1.7 (0.8, 3.7) 0.9 (0.3, 2.2) 0.6 (0.3,1.02) 1.2 (0.7, 1.9) 1.2 (0.7, 1.9) 2.0 (1.3, 3.3) 0.8 (0.5, 1.4) 0.8 (0.4, 1.4)
MPO 2.1 (0.95,4.6) 2.2 (1.04,4.8) 0.9 (0.3, 2.3) 0.9 (0.5, 1.5) 1.4 (0.9, 2.3) 1.0 (0.7, 1.9) 1.5 (0.9, 2.4) 1.0 (0.6, 1.8) 1.0 (0.6, 1.8)
IL-1β 1.2 (0.5, 2.9) 1.0 (0.4, 2.4) 1.8 (0.8, 4.1) 0.9 (0.5, 1.5) 1.0 (0.6, 1.6) 1.1 (0.7, 1.9) 1.7 (1.1, 2.7) 1.1 (0.6, 1.8) 1.2 (0.7, 2.1)
IL-6 1.1 (0.4, 2.6) 0.9 (0.4, 2.2) 0.9 (0.4, 2.4) 1.3 (0.8, 2.1) 1.2 (0.7, 1.9) 0.9 (0.6, 1.6) 2.1 (1.3, 3.4) 1.1 (0.7, 1.9) 1.1 (0.7, 1.9)
IL-6R 1.3 (0.6, 2.0) 1.5 (0.7, 3.4) 1.3 (0.5, 3.2) 1.1 (0.6, 1.7) 1.6 (1.02,2.6) 1.1 (0.7, 1.9) 2.0 (1.2, 3.2) 1.2 (0.7, 2.0) 1.0 (0.6, 1.8)
TNF-α 1.6 (0.7, 3.8) 1.1 (0.5, 2.4) 2.0 (0.9, 4.7) 1.0 (0.6, 1.6) 0.7 (0.4, 1.2) 1.1 (0.7, 1.9) 1.8 (1.1, 2.9) 0.9 (0.6, 1.6) 1.3 (0.8, 2.2)
TNF-R1 1.1 (0.5, 2.7) 2.1 (0.97,4.7) 1.0 (0.4, 2.6) 1.6 (1.01,2.5) 1.8 (1.1, 2.8) 0.9 (0.6, 1.6) 1.1 (0.7, 1.9) 0.8 (0.5, 1.4) 1.0 (0.5, 1.7)
TNF-R2 1.4 (0.6, 3.2) 2.1 (0.99,4.6) 1.5 (0.7, 3.6) 1.2 (0.8, 2.0) 1.6 (1.02,2.5) 0.9 (0.5, 1.5) 1.1 (0.6, 1.8) 1.1 (0.7, 1.9) 0.6 (0.3, 1.2)
IL-8 (CXCL8) 1.7 (0.8, 3.9) 1.5 (0.7, 3.2) 1.4 (0.6, 3.4) 1.0 (0.6, 1.7) 0.8 (0.5, 1.3) 1.1 (0.7, 1.8) 1.2 (0.7, 2.0) 0.8 (0.5, 1.4) 1.4 (0.8, 2.3)
MCP-1 (CCL2) 0.8 (0.3, 2.1) 1.7 (0.8, 3.9) 1.0 (0.4, 2.6) 1.2 (0.7, 2.0) 0.9 (0.5, 1.4) 0.9 (0.5, 1.5) 1.1 (0.7, 1.9) 0.4 (0.2, 0,8) 1.2 (0.7, 2.0)
MCP-4 (CCL13) 2.6 (1.2, 5.9) 2.5 (1.2, 5.4) 1.7 (0.7, 4.0) 1.2 (0.7, 1.9) 0.9 (0.5, 1.5) 1.2 (0.7, 1.9) 1.3 (0.7, 2.1) 0.7 (0.4, 1.3) 1.0 (0.6, 1.8)
MIP-1β (CCL4) 1.2 (0.5, 2.7) 2.3 (1.1, 4.9) 1.1 (0.5, 2.8) 0.9 (0.5, 1.5) 1.2 (0.8, 2.0) 1.1 (0.7, 1.9) 1.0 (0.6, 1.7) 1.7 (1.03,2.7) 0.8 (0.4, 1.4)
RANTES (CCL5) 1.8 (0.8, 4.0) 1.8 (0.8, 3.9) 1.4 (0.5, 3.4) 1.6 (1.02,2.6) 1.8 (1.1, 2.8) 1.2 (0.7, 2.0) 1.7 (1.01,2.7) 1.1 (0.6, 1.8) 1.1 (0.7, 2.0)
I-TAC (CXCL11) 2.5 (1.2, 5.5) 1.2 (0.6, 2.8) 1.7 (0.7, 4.0) 1.1 (0.6, 1.7) 0.9 (0.6, 1.5) 1.0 (0.6, 1.8) 1.2 (0.7, 1.9) 0.7 (0.4, 1.2) 1.1 (0.6, 1.9)
ICAM-1 (CD54) 1.5 (0.7, 3.4) 1.3 (0.6, 3.0) 1.6 (0.7, 3.8) 0.7 (0.4, 1.2) 1.2 (0.7, 1.9) 0.6 (0.3, 1.1) 1.4 (0.8, 2.2) 1.4 (0.8, 2.2) 1.2 (0.7, 2.1)
ICAM-3 (CD50) 1.7 (0.7, 3.9) 1.3 (0.6, 3.1) 1.4 (0.6, 3.5) 1.0 (0.6, 1.6) 1.5 (0.97,2.5) 1.1 (0.7, 1.9) 1.6 (1.00,2.6) 1.0 (0.6, 1.8) 0.7 (0.4, 1.2)
VCAM-1 (CD106) 1.4 (0.6, 3.2) 1.2 (0.5, 2.9) 0.9 (0.4, 2.4) 1.1 (0.7, 1.8) 1.1 (0.7, 1.8) 0.6 (0.3, 1.1) 1.6 (0.98,2.6) 1.5 (0.9, 2.4) 1.1 (0.6, 1.8)
E-SEL (CD62E) 1.8 (0.8, 4.1) 1.7 (0.9, 3.8) 0.8 (0.3, 2.1) 1.3 (0.8, 2.0) 1.4 (0.8, 2.2) 1.2 (0.8, 2.0) 2.4 (1.5, 3.9) 1.8 (1.1, 3.0) 1.4 (0.8, 2.3)
MMP-1 1.1 (0.4, 2.6) 0.6 (0.2, 1.6) 0.6 (0.2, 1.8) 1.1 (0.7, 1.8) 1.2 (0.7, 1.9) 0.7 (0.4, 1.2) 1.4 (0.9, 2.3) 0.9 (0.5, 1.5) 1.4 (0.8, 2.3)
MMP-9 1.4 (0.6, 3.2) 1.4 (0.6, 3.2) 1.1 (0.5, 2.8) 0.9 (0.6, 1.6) 1.6 (0.99,2.5) 0.9 (0.6, 2.6) 1.1 (0.7, 1.8) 1.0 (0.6, 1.7) 1. 1 (0.6, 1.8)
VEGF 1.5 (0.7, 3.5) 2.1 (0.98,4.6) 2.0 (0.9, 4.7) 0.9 (0.6, 1.6) 1.1 (0.6, 1.7) 09 (0.6, 1.6) 1.4 (0.9, 2.4) 1.0 (0.6, 1.7) 0.8 (0.4, 1.4)
VEGF-R1 0.7 (0.3, 1.9) 1.0 (0.4, 2.5) 0.5 (0.2, 1.6) 1.3 (0.8, 2.1) 1.1 (0.7, 1.8) 0.6 (0.3,1.02) 0.9 (0.5, 1.5) 0.7 (0.4, 1.3) 0.6 (0.4, 1.2)
VEGF-R2 1.8 (0.8, 3.9) 1.2 (0.5, 2.7) 1.0 (0.4, 2.4) 1.2 (0.8, 2.0) 1.5 (0.96,2.4) 0.9 (0.5, 1.5) 2.2 (1.4, 3.5) 1.5 (0.9, 2.5) 1.0 (0.6, 1.7)
IGFBP-1 0.8 (0.3, 2.1) 0.4 (0.1, 1.3) 0.8 (0.3, 2.2) 1.3 (0.8, 2.0) 1.4 (0.9, 2.3) 0.9 (0.5, 1.5) 0.9 (0.5, 1.5) 1.2 (0.7, 2.0) 0.8 (0.5, 1.5)

Total Protein 1.0 (0.4, 2.4) 0.7 (0.3, 1.8) 0.4 (0.1, 1.3) 1.1 (0.7, 1.8) 0.8 (0.5, 1.3) 0.8 (0.5, 1.4) 0.9 (0.5, 1.5) 0.6 (0.4, 1.1) 1.1 (0.6, 1.8)

N specimens 28 29 25 100 100 91 91 87 78