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LD50 (μM) values for select compounds against HEK293 cells with control (staurosporine), cLogD values,35 and aqueous solubilities (μg/mL ± SD).
| Compound | LD50 (μm) | cLogD | Solubility (μg/mL ± SD) |
|---|---|---|---|
| Staurosporine | < 3 | ND | ND |
| MAL2-11B tetrazole |
> 200 | 3.4 | 53.7 ± 1.7 |
| LR340-006 | 166 ± 2 | 3.9 | ND |
| ML282-56 | 162 ± 3 | 3.9 | 14.4 ± 0.5 |
| SMAL | 137 ± 1 | 4.4 | 62.4 ± 3.1 |
