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Analysis of apoptolidin toxicity in H292 cell line. A) Dependence of cytotoxic and cytostatic effects of apoptolidin A on cell confluency as measured by initial number of cells per well on a 96 well plate; B) Effect of cell growth media of varying glucose concentrations on apoptolidin A cytotoxicity; C) Cell viability assay for apoptolidin A (1) and Cy3 apoptolidin A (11); and D) apoptolidin H (3), Cy3 apoptolidin H (12) and BNE-Cy3 (10) evaluated using optimized conditions.
