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Pharmacokinetics of RA-2. (A) RA-2 plasma calibration curve with concentrations ranging from 10 nM to 1 µM (r2 = 0.9995). (B) RA-2 plasma concentrations following intraperitoneal application of 30 mg/kg (n = 3, mice). (C) Tissue concentrations 1 hour after intraperitoneal administration of RA-2 30 mg/kg (n = 3, mice). (D) Time course of tissue concentrations after intraperitoneal administration of RA-2 30 mg/kg (n = 3, mice). Data points are mean ± S.D.
