Table 4. Sensitivity, specificity, PPV, NPV, likelihood ratio (+/-) of H. pylori 1-hr RUT, 24-hr RUT of patients with or without PPI consumption.
| Group | No. of patients | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Likelihood ratio |
|
|---|---|---|---|---|---|---|---|
| + | − | ||||||
| 1-hr RUT | 530 | ||||||
| With PPI | 73/98 (74.4) | 214/228 (93.8) | 73/87 (83.9) | 214/239 (89.5) | 5.2 | 0.1 | |
| Without PPI | 107/116 (92.2) | 75/88 (85.2) | 107/120 (89.1) | 75/84 (89.2) | 8.2 | 0.1 | |
| ≤24-hr RUT | 530 | ||||||
| With PPI | 80/98 (81.6) | 184/228 (80.7) | 80/124 (64.5) | 184/202 (91.0) | 1.8 | 0.1 | |
| Without PPI | 109/116 (93.9) | 65/88 (73.8) | 109/132 (82.5) | 65/72 (90.2) | 4.7 | 0.1 | |
PPV, positive predictive value; NPV, negative predictive value; RUT, rapid urease test; PPI, proton pump inhibitors.