Table 2.

Spleen and thymus characteristics wild-type (+/+), heterozygous (fatt/+) and obese (fatt/fatt) mice $

Sex	Males			Females
Genotype	+/+	fatt/+	fatt/fatt	+/+	fatt/+	fatt/fatt
N	5	8	8	6	7	4
Spleen (mg)	132.13 ± 26.98	152.5 ± 33.91	149.20 ± 57.13	99.77 ± 17.46	113.51 ± 22.26	125.72 ± 43.77
Spleen (mg/body weight)	5.73 ± 1.25	6.54 ± 1.37	3.26 ± 1.37*##	6.05 ± 1.24	6.20 ± 1.53	3.26 ± 1.20**##
Thymus (mg)	46.30 ± 9.8	38.18 ± 14.38	67.12 ± 18.43##	42.60 ± 4.8	42.94 ± 8.92	68.04 ± 17.27**##
Thymus (mg/body weight)	2.03 ± 0.37	1.62 ± 0.76	1.37 ± 0.43	2.45 ± 0.33	2.15 ± 0.27	1.63 ± 0.52**#G
Age (days)	74.50 ± 3.0	75.80 ± 3.74	75.83 ± 2.86	72.17 ± 1.60	73.14 ± 3.24	73.00 ± 4.00

Results are displayed as average ± standard deviation

WAT white adipose tissue, BAT brown adipose tissue

Tukey’s HSD test used in all analysis unless noted, Games–Howell test (G): significance is denoted as * P < 0.05 versus +/+, ** P < 0.001 versus +/+, ^# P < 0.05 versus fatt/+, ^## P < 0.001 versus fatt/+. Differences are not significant unless noted