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Participation of Lyn in TLR4 signaling. Lyn kinase either associates constitutively with proteins or associates with, and phosphorylates, indicated proteins after stimulation of cell with LPS. These events regulate positively or negatively TLR4-induced signaling (left and right side of the figure, respectively). Arrows indicate domains of Lyn most likely involved in binding of indicated proteins. The molecules are drawn not to scale
