Figure 3. Quantifying calcium flux patterns within individual responding T cells.
The empirical cumulative distribution function (ECDF) for the time to first calcium oscillation was analysed for anti-CD3 (solid blue line), anti-CD3 + antiCD28(adh) (solid black line), anti-CD3 + anti-CD28(sens) (thick solid black line), anti-CD3(Fab) (dotted blue line) and CD3(Fab) + anti-CD28(adh) (dotted black line) for the total population (a) and the responding population only (b). The time between first and second oscillation was further analysed (c).
