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Temporal lobe seizures modulate cerebellar activity. An example temporal lobe seizure recorded in the hippocampus (a), which produced changes in the cerebellar EEG (b) and in the firing rate of a juxtacellularly recorded Purkinje cell over the course of the seizure (c) as well as on a shorter time scale (d). Green trace denotes detected Purkinje cell spikes. Scale bars: a, 1 mV; b, 0.5 mV; a−c, 10 s; d, 0.5 mV or 0.1 kHz change in firing rate, 0.1 s.
