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. 2014 Nov;93(11):1163–1169. doi: 10.1177/0022034514551769

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Figure 1. — Sympathetic nervous system–regulated orthodontic tooth movement (OTM) partially depends on β-2 adrenergic receptor (Adrb2). (A, B) Analysis of the OTM distance by micro–computed tomography scanning and hematoxylin and eosin staining. (A) Superior cervical ganglionectomy (SCGx) decreased OTM distance after 14 d of force application in rats (n = 8). (B) OTM distance decreased in the Adrb1/2^-/- group compared to the WT group after 7 d of force application in mice (n = 14). WT, wild type. Hematoxylin and eosin staining shows the integrity of the periodontal tissue around the 2 molars after tooth movement. The bar indicates 500 μm. M1, the first molar. M2, the second molar. Arrows indicate OTM distance. ^* p < .05. ^** p < .001.