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. 2015 Jan 7;13:1. doi: 10.1186/1477-7827-13-1

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© Blaha et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of CNP on spontaneous and FSH-induced maturation of pig cumulus-enclosed oocytes. (a) Effect of CNP (100 nM) on spontaneous maturation of oocytes. (b) Effect of CNP on maturation of oocytes induced by FSH (1 IU/ml). GV, germinal vesicle; GVBD, germinal vesicle breakdown; MII, metaphase II. Significant differences were only found between FSH and FSH + CNP groups after 24 h of culture. Approximately 75 COCs were included in each group.