Table 1.
Risk factor | Relative risk |
---|---|
Age ≥45 years | 5–6× |
Obesity: body mass index ≥30 kg/m2 | 4–5× |
Overweight: body mass index ≥25, <30 kg/m2 | 2–3× |
Hypertension | 2–3× |
Hyperlipidemia | 4× |
Family history | |
One first-degree relative or two second-degree relatives | 2–3× |
Two first-degree relatives, or one first-degree and two second-degree relatives | 5–6× |
Genetic variant carrier | |
Heterozygous | 1.1–1.4× |
Homozygous | Up to 10× |