Table 1.
Term | Definition |
---|---|
Moderate – severe ulcerative colitis | Mayo score 6–12 (range 0–12) |
Partial Mayo score | Mayo score without endoscopic sub-score (range 0–9) |
Clinical response | Decrease from baseline of ≥3 points in total Mayo score, and at least 30%, with decrease in rectal bleeding sub-score of ≥1 point (or an absolute sub-score of 0 or 1) |
Clinical remission | Total Mayo score of ≤2, with no individual sub-score >1 |
Mucosal healing | Endoscopy sub-score of 0 or 1 |
Clinical flare | Increase from baseline in partial Mayo score of ≥2 points with absolute partial Mayo score ≥4, or absolute partial Mayo score ≥7 |