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. 2014 Nov 24;171(23):5417–5430. doi: 10.1111/bph.12857

Figure 4.

Figure 4

Time course of DOP receptor-induced EAAT1 and EAAT2 expression in the astrocytes. (A) Quantitative PCR analysis showing that UFP-512 induced EAAT1 and EAAT2 mRNA expression in a time-dependent manner with expression reaching peak at 12 h. (B) Western blot showing that UFP-512 induced EAAT1 and EAAT2 protein production in a time-dependent manner with production reaching peak at 24 h. C, non-treatment; U, 10 μM UFP-512. *P < 0.05; **P < 0.01. Note that UFP-512 induced both EAAT1 and EAAT2 mRNA as well as protein expression in a time-dependent manner.