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Model parameters of warfarin pharmacokinetics model
| Parameter | Value |
|---|---|
| βCL/F (l h−1) | 0.15 |
| βV/F (l) | 8.00 |
| βka (l h−1) | 1.00 |
 |
0.07 |
 |
0.02 |
 |
0.60 |
| σ2 | 0.01 |
Abbreviations are as follows: CL/F, apparent clearance of the warfarin; ka, constant of absorption of the warfarin; V/F, apparent volume of distribution of the warfarin; β, fixed effects; σ2, residual variance; ω2, interindividual variance.
