Table 1.

Representative model systems used to inform patient care

Citation	Model/patient population
Chu et al. [10]	Decision support to facilitate management of patients with acute GI bleeding
Schurink et al. [11]	Bayesian decision-support system for diagnosing ventilator-associated pneumonia
Rees et al. [12]	Physiological models and decision theory to select appropriate ventilator settings
Freedman et al. [13]	Wilkoff mathematical model to assess pacemaker chronotropic response
Picchini et al. [14]	Mathematical model of the euglycaemic hyperinsulinaemic clamp
Hann et al. [15]	Cardiac model of non-linear valve law to guide ventricular interaction dynamics
Jornil et al. [16]	Dose adjustment of nortriptyline based on activity of CYP3A4 and CYP2D6