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. 2015 Jan 14;5:740. doi: 10.3389/fmicb.2014.00740

Table 4.

Misdiagnosis of 11 patients.

Case no./References Bone and joints Misdiagnosis Delay time Treatment before diagnosis Method of definite diagnosis Treatment after diagnosis Outcome
22/Matsushita and Suzuki, 1985 T9, T10, T11 Metastatic cancer 7 months Irradiation ATT, immobilization Histopathology Surgery, 5-FC+AMB Response
Tuberculosis
28/Baldwin et al., 1988 Right ilium Musculoskeletal pain 6 weeks Acetaminophen Histopathology culture Surgery, AMB504 mg+5-FC224 g Response
29/Govender et al., 1988 Left femur Bacterial osteomyelitis NA Antibiotics immobilization Culture Surgery Response
32/Stead et al., 1988 Left elbow, right knee and right elbow Tuberculosis 18 weeks ATT, antibiotics, physiotherapy Culture Surgery AMB+ketoconazole Response
48/Schmidt et al., 1995 Left femur, skull, left humerus, C5, C6 Tuberculosis 16 days ATT Culture AMB+5-FC+Flu Response
54/Liu, 1998 Right humerus right tibia Bacterial infection >1 months Incision and drainage Histopathology culture Surgery+AMB Failure
57/Jain et al., 1999 T6 Tuberculosis >3 months ATT Histopathology culture AMB+5-FC Response
60/Prendiville et al., 2000 Sphenoid sinus, skull base Tolosa-Hunt syndrome >2 months Prednisone Histopathology culture Surgery+Flu+AMB Response
65/Gupta et al., 2003 T1, T2, T3 Tuberculosis NA ATT Histopathology Surgery Failure
69/Goldshteyn et al., 2006 Left humeral head An avascular necrosis NSAIDs Culture AMB+Flu Response
77/Agadi et al., 2010 L5, sternum Tuberculosis NA ATT Histopathology culture AMB Failure
82/Corral et al., 2011 Right parietal bone Soft tissue infection >10 months Antibiotics Histopathology culture Surgery+AMB+Flu Response
88/Jain et al., 2013 Sternal Gastroesophageal reflux disease NA Antacids Histopathology culture Surgery+Flu+AMB+5-FC Response

ATT, antituberculosis therapy; 5-FC, 5-fluorocytosine; AMB, amphotericin B; NA, not available; Flu, fluconazole; NSAIDs, nonsteroidal anti-inflammatory medications.