Table I.
MicroRNA signature differentiating MDS versus Normal Controls (NC).
| MicroRNA | Parametric P value |
Fold change |
Chromosomal location |
|---|---|---|---|
| MIR222 | 0·0020831 | 3·81 | Xp11.3 |
| MIR10A | 0·0018187 | 3·37 | 17q21.32 |
| MIR196A | 6·66E-05 | 3·04 | 17q21.32 |
| MIR320 | <1e-07 | 2·12 | 8p21.3 |
| MIR100 | 0·0298715 | 1·51 | 11q24.1 |
| MIR124 | 0·0009909 | 0·60 | 8p23.1 |
| MIR206 | 0·0093797 | 0·59 | 6p12.2 |
| MIR146A | 0·0356401 | 0·57 | 5q34 |
| MIR150 | 0·0365018 | 0·54 | 19q13.33 |
| MIR326 | 0·0001276 | 0·51 | 11q13.14 |
| MIRLET7E | <1e-07 | 0·46 | 19q13.41 |
| MIR197 | 0·000754 | 0·33 | 1p13.3 |
| MIR875-5P | <1e-07 | 0·02 | 8q22.2 |
This 13 microRNA signature was predictive (misclassification error rate after 10-fold CV, <0·01). Red: up-regulated microRNAs. Green: down-regulated microRNAs.