TABLE 1.
Correlation between IgG1 and IgG3 responses to merozoite antigens of P. falciparum
Antigen | Antibody | Correlation coefficienta |
|||||||
---|---|---|---|---|---|---|---|---|---|
MSP1-19 |
MSP2 3D7 |
MSP2 FC27 |
AMA-1 |
||||||
IgG1 | IgG3 | IgG1 | IgG3 | IgG1 | IgG3 | IgG1 | IgG3 | ||
MSP1-19 | IgG1 | ||||||||
IgG3 | 0.58 | ||||||||
MSP2 3D7 | IgG1 | 0.38 | 0.38 | ||||||
IgG3 | 0.36 | 0.44 | 0.78 | ||||||
MSP2 FC27 | IgG1 | 0.37 | 0.39 | 0.75 | 0.74 | ||||
IgG3 | 0.34 | 0.42 | 0.71 | 0.79 | 0.87 | ||||
AMA-1 | IgG1 | 0.37 | 0.48 | 0.71 | 0.70 | 0.69 | 0.73 | ||
IgG3 | 0.21 | 0.45 | 0.56 | 0.68 | 0.58 | 0.66 | 0.65 |
Correlation coefficients were determined by Spearman's method. All correlations are significant at a P value of <0.001.