Figure 5. HPV E6 and miR-9 were both positive regulators of NIKS cell motility.

(A) HPV16 E6 expression led to increased mobility of NIKS cells as compared with control cells expressing vehicle vector. (B) Transient overexpression of miR-9 or knockdown of miR-9 targets (FSTL1 or ALCAM) by siRNA led to increased mobility of NIKS cells as compared with the negative control RNA transfection.