Table 2. Univariate and multivariable analysis of disease-free survival for surgically treated NSCLC patients after adjuvant chemotherapy.
| Variables | Item | Univariate | Multivariable* | ||||
|---|---|---|---|---|---|---|---|
| Hazard Rate Ratio | 95% Confidence Interval | P value | Hazard Rate Ratio | 95% Confidence Iinterval | P value | ||
| Age (y) | >70 | 1.46 | (0.78, 2.72) | 0.240 | - | - | - |
| ≤70 | 1.00 | - | |||||
| Sex | Male | 0.93 | (0.47, 1.83) | 0.822 | - | - | - |
| Female | 1.00 | - | |||||
| Grade | III | 1.38 | (0.39, 4.89) | 0.620 | - | - | - |
| II | 1.82 | (0.77, 4.34) | 0.174 | - | - | - | |
| I | 1.00 | - | |||||
| T status‡ | T3 | 0.54 | (0.19, 1.54) | 0.249 | - | - | - |
| T2 | 0.76 | (0.36, 1.60) | 0.466 | - | - | - | |
| T1 | 1.00 | - | |||||
| N status‡ | N2 | 3.60 | (1.74, 7.43) | 0.001 | 2.97 | (1.42, 6.25) | 0.004 |
| N1 | 3.43 | (1.59, 7.41) | 0.002 | 2.69 | (1.21, 5.98) | 0.015 | |
| N0 | 1.00 | 1.00 | |||||
| Histology | Squamous cell carcinoma | 1.26 | (0.67, 2.37) | 0.478 | - | - | - |
| Adenocarcinoma | 1.00 | - | |||||
| Performance | 1 | 1.66 | (0.87, 3.17) | 0.125 | - | - | - |
| 0 | 1.00 | - | |||||
| Smoking status | Current | 0.85 | (0.42, 1.71) | 0.640 | - | - | - |
| Former | 0.97 | (0.47, 2.01) | 0.939 | - | - | - | |
| Never | 1.00 | - | |||||
| Id1 | High | 0.37 | (0.20, 0.66) | 0.001 | 0.49 | (0.27, 0.91) | 0.024 |
| Low | 1.00 | 1.00 | |||||
*
Variables with p<0.1 were included in the multivariable analysis.
‡
T, N statuses were based on the AJCC-TNM staging system [23].