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. 2014 Nov 3;5(22):11017–11028. doi: 10.18632/oncotarget.2669

Table 2. Differentially expressed genes in normal and colorectal tumor tissue. Gene expression was compared: pre, before hepatic pedicle clamping; post, after clamping; 10', 10 minutes after resection; 20', 20 minutes after resection; and 45', 45 minutes after resection.

Normal colon tissue Colorectal tumor tissue
Pre vs 10' Pre vs 45' Pre vs 10' Pre v. 45'
Probe ID Gene Protein and function p-value Log-fold change p-value Log-fold change p-value Log-fold change p-value Log-fold change
201289_at CYR61 Cysteine-rich angiogenic inducer 61; extracellular matrix-associated signaling protein that plays important roles in tissue repair 1.57E-18 2.49 2.84E-22 2.55 0.00000133 1.41 3.96E-08 1.59
202988_s_at RGS1 Regulator of G-protein signaling 1; attenuates signaling activity of G-proteins 4.21E-21 2.34 5.05E-25 2.39 1.81E-09 1.57 7.62E-12 1.91
216834_at 1.65E-22 2.33 8.96E-25 2.36 3.06E-09 1.42 5.2E-12 1.76
201694_s_at EGR1 Early growth response 1; transcription factor 1.92E-12 2.02 1.79E-18 2.26 . . . .
227404_s_at 1.4E-10 1.98 2.57E-16 2.32 . . . .
201739_at SGK1 Serum/glucocorticoid regulated kinase 1; activates potassium, sodium and chloride channels 4.03E-14 2.09 2.74E-16 2.21 . . . .
209189_at FOS FBJ murine osteosarcoma viral oncogene homolog; transcription factor involved in cell proliferation, differentiation, survival, hypoxia and angiogenesis 1.26E-18 2.77 9.3E-25 3.19 . . . .
218541_s_at C8orf4 Chromosome 8 open reading frame 4; uncharacterized protein 2.39E-12 2 3.64E-15 2.01 . . . .
201041_s_at DUSP1 Dual specificity phosphatase 1; dephosphorylates MAP kinase MAPK1/ERK2 1.21E-17 1.85 3E-23 2.15 . . 0.0000115 1.14
219727_at DUOX2 Dual oxidase 2; plays a role in antimicrobial defense at the mucosal surface 3.36E-08 -1.88 2.24E-10 -2.14 0.000497 -1.51 0.0000133 -1.82
219795_at SLC6A14 Solute carrier family 6 (amino acid transporter), member 14; mediates the uptake of a broad range of amino acids 0.0000101 -1.87 0.00000036 -2.16 0.0109 -1.2 0.000316 -1.75
205844_at VNN1 Vanin 1; amidohydrolase recycling pantothenic acid (vitamin B5) and releasing cysteamine 0.000102 -1.62 0.000000164 -2.17 . . . .