Table 1. Statistical significance of time- and dose-dependent effects of metformin and IAA94 on U87 cell survival.
Time | Metformin (mM) | IAA94 (μM) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 | 3 | 10 | 30 | 50 | 1 | 10 | 30 | 100 | 300 | |
24h | n.s. | n.s. | n.s. | <0.0001 | <0.0001 | n.s. | n.s. | n.s. | <0.0001 | <0.0001 |
48h | <0.05 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | n.s. | n.s. | n.s. | <0.0001 | <0.0001 |
72h | <0.0005 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | n.s. | n.s. | n.s. | <0.0001 | <0.0001 |
Data are obtained comparing treated cell viability with vehicle-treated control cells, in MTT assay.
One-way ANOVA, followed by Dunnett's post hoc test.
n.s.: not significant.