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The SCFTIR1-Aux/IAA-ARF auxin-response pathway. A cartoon of the interactions in the canonical nuclear auxin receptor complex and its effects on auxin-induced transcription. The TIR1/AFB interaction with the Aux/IAA co-receptor/transcriptional repressors increases at higher auxin concentrations, promoting Aux/IAA ubiquitination and degradation. The transcriptional activity of activator ARFs is modulated by the levels of Aux/IAAs and repressor ARFs.
