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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Physiol Plant. 2014 May;151(1):52–61. doi: 10.1111/ppl.12135

Fig. 2.

Fig. 2

Fine-tuning the transcriptional auxin response through the SCFTIR1-Aux/IAA-ARF pathway. The modular nature of the members of the SCFTIR1-Aux/IAA-ARF pathway may allow for specific outputs of pathway activation, depending on the cellular expression of family members with distinct interaction affinities. In Arabidopsis there are 6 auxin F-box receptors (TIR1 and AFB1–5), 29 Aux/IAA co-receptors, 5 activator ARFs (ARF5–8 and ARF19) and 18 repressor ARFs (of which ARF2, 12, 14, 15, 19, 20, 21 and 22 contain recognized transcriptional repression domains and the remaining ten may have as yet undescribed transcription factor activities). Red and green arrows indicate theoretical negative and positive regulation, respectively.