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. 2014 Oct 29;5(1):30–38. doi: 10.1159/000368826

Table 1.

Reported cases of bucillamine-induced crescent formation

Year Initial diagnosis Clinical manifestation IF study EM study ANCA Outcome Treatment Reference

1993 RA RPGN negative no EDD negative improved prednisolone, cyclophosphamide 13

1993 RA NS without hematuria negative mesangial EDD NR improved prednisolone 14

2012 RA RPGN, NS IgG, C3, C1q subepithelial EDD negative improved prednisolone, cyclophosphamide present case

RA = Rheumatoid arthritis; EDD = electron-dense deposit; NR = not reported.