Skip to main content
. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: JAMA Otolaryngol Head Neck Surg. 2014 Dec 1;140(12):1101–1109. doi: 10.1001/jamaoto.2014.2530

Table 1.

Characteristics of SEER Head and Neck Melanoma by SLNB Treatment Pre- and Post- Matchinga

HN Melanoma Pre-Matching (n=7266) HN Melanoma Post-Matching (n=5102)

Covariate Subcategory No SNB 3381(46) Yes SNB 3885(54) pb dc No SNB 2551(50) Yes SNB 2551(50) dc
Age Categories 15-44 229 (30) 547 (70) <.001 221 (50) 221 (50)
45-54 257 (31) 574 (69) 247 (50) 247 (50)
55-64 534 (38) 881 (62) 489 (50) 489 (50)
65-74 861 (47) 985 (53) 719 (50) 719 (50)
75-84 1500 (63) 898 (37) 875 (50) 875 (50)

Age 68.8 ± 13.7 61.6 ± 15.1 <.001 .475 66.2 ± 14.3 66.2 ± 13.8 .006

Marital Status Married 1874 (41) 2683 (69) <.001 .295 1637 (51) 1601 (49) .031
Not 1507 (56) 1202 (44) 914 (49) 950 (51)

Race White 3259 (46) 3841 (54) <.001 .234 2516 (50) 2517 (50) .004
Other 122 (74) 44 (26) 35 (51) 34 (49)

Sex Female 888 (49) 935 (51) .03 .051 617 (49) 637 (51) .018
Male 2493 (46) 2950 (54) 1934 (50) 1914 (50)

Breslow Thickness <=1mm 1184 (63) 694 (37) <.001 869 (65) 473 (35)
>1 to 2mm 1088 (40) 1658 (60) 794 (42) 1098 (58)
>2 to 4mm 636 (40) 957 (60) 484 (43) 630 (57)
>4mm 473 (45) 576 (55) 404 (54) 350 (46)

Breslow 2.2 ± 2.0 2.4 ± 1.9 <.001 .108 2.3 ± 2.1 2.4 ± 1.8 .010

H&N Site Face 2124 (50) 2159 (50) <.001 .146 1520 (50) 1514 (50) .005
Scalp/Neck 1257 (42) 1726 (58) 1031 (50) 1037 (50)

Tumor Registry <Median 1498 (51) 1446 (49) <.001 .147 1066 (51) 1041 (49) .020
>Median 1883 (44) 2439 (56) 1485 (50) 1510 (50)

Major Histology Groups Desmoplastic 198 (45) 243 (55) <.001 .016 165 (52) 149 (48) .026
LM 378 (59) 262 (41) .177 222 (50) 220 (50) .003
NOS 1488 (47) 1667 (53) .022 1132 (51) 1107 (49) .020
Nodular 418 (39) 646 (61) .115 353 (48) 377 (52) .025
SS 687 (46) 823 (54) .021 518 (50) 528 (50) .010
Other 212 (46) 244 (54) .000 161 (49) 170 (51) .015

Ulceration No 2729 (48) 2935 (52) <.001 .120 2013 (50) 1987 (50) .024
Yes 652 (41) 950 (59) 538 (49) 564 (51)

1st Malignancy No 915 (55) 754 (45) <.001 .194 645 (51) 621 (49) .024
Yes 2466 (44) 3131 (56) 1906 (50) 1930 (50)
a

Reported as frequency (percent) for nominal variables, and mean +− standard deviation (range) for continuous variables

b

Chi-square and p-value for dichotomous variables; two-sample t-test and p-value for continuous variables; <0.05 considered significant.

c

Standardized difference of the means (absolute value); <0.1 considered to represent good balance.

Abbreviations: SLNB=sentinel lymph node biopsy, HN= Head and Neck, LM=lentigo maligna, NOS=Melanoma NOS, SS=superficial spreading