Table 1.
HN Melanoma Pre-Matching (n=7266) | HN Melanoma Post-Matching (n=5102) | |||||||
---|---|---|---|---|---|---|---|---|
Covariate | Subcategory | No SNB 3381(46) | Yes SNB 3885(54) | pb | dc | No SNB 2551(50) | Yes SNB 2551(50) | dc |
Age Categories | 15-44 | 229 (30) | 547 (70) | <.001 | 221 (50) | 221 (50) | ||
45-54 | 257 (31) | 574 (69) | 247 (50) | 247 (50) | ||||
55-64 | 534 (38) | 881 (62) | 489 (50) | 489 (50) | ||||
65-74 | 861 (47) | 985 (53) | 719 (50) | 719 (50) | ||||
75-84 | 1500 (63) | 898 (37) | 875 (50) | 875 (50) | ||||
Age | 68.8 ± 13.7 | 61.6 ± 15.1 | <.001 | .475 | 66.2 ± 14.3 | 66.2 ± 13.8 | .006 | |
Marital Status | Married | 1874 (41) | 2683 (69) | <.001 | .295 | 1637 (51) | 1601 (49) | .031 |
Not | 1507 (56) | 1202 (44) | 914 (49) | 950 (51) | ||||
Race | White | 3259 (46) | 3841 (54) | <.001 | .234 | 2516 (50) | 2517 (50) | .004 |
Other | 122 (74) | 44 (26) | 35 (51) | 34 (49) | ||||
Sex | Female | 888 (49) | 935 (51) | .03 | .051 | 617 (49) | 637 (51) | .018 |
Male | 2493 (46) | 2950 (54) | 1934 (50) | 1914 (50) | ||||
Breslow Thickness | <=1mm | 1184 (63) | 694 (37) | <.001 | 869 (65) | 473 (35) | ||
>1 to 2mm | 1088 (40) | 1658 (60) | 794 (42) | 1098 (58) | ||||
>2 to 4mm | 636 (40) | 957 (60) | 484 (43) | 630 (57) | ||||
>4mm | 473 (45) | 576 (55) | 404 (54) | 350 (46) | ||||
Breslow | 2.2 ± 2.0 | 2.4 ± 1.9 | <.001 | .108 | 2.3 ± 2.1 | 2.4 ± 1.8 | .010 | |
H&N Site | Face | 2124 (50) | 2159 (50) | <.001 | .146 | 1520 (50) | 1514 (50) | .005 |
Scalp/Neck | 1257 (42) | 1726 (58) | 1031 (50) | 1037 (50) | ||||
Tumor Registry | <Median | 1498 (51) | 1446 (49) | <.001 | .147 | 1066 (51) | 1041 (49) | .020 |
>Median | 1883 (44) | 2439 (56) | 1485 (50) | 1510 (50) | ||||
Major Histology Groups | Desmoplastic | 198 (45) | 243 (55) | <.001 | .016 | 165 (52) | 149 (48) | .026 |
LM | 378 (59) | 262 (41) | .177 | 222 (50) | 220 (50) | .003 | ||
NOS | 1488 (47) | 1667 (53) | .022 | 1132 (51) | 1107 (49) | .020 | ||
Nodular | 418 (39) | 646 (61) | .115 | 353 (48) | 377 (52) | .025 | ||
SS | 687 (46) | 823 (54) | .021 | 518 (50) | 528 (50) | .010 | ||
Other | 212 (46) | 244 (54) | .000 | 161 (49) | 170 (51) | .015 | ||
Ulceration | No | 2729 (48) | 2935 (52) | <.001 | .120 | 2013 (50) | 1987 (50) | .024 |
Yes | 652 (41) | 950 (59) | 538 (49) | 564 (51) | ||||
1st Malignancy | No | 915 (55) | 754 (45) | <.001 | .194 | 645 (51) | 621 (49) | .024 |
Yes | 2466 (44) | 3131 (56) | 1906 (50) | 1930 (50) |
Reported as frequency (percent) for nominal variables, and mean +− standard deviation (range) for continuous variables
Chi-square and p-value for dichotomous variables; two-sample t-test and p-value for continuous variables; <0.05 considered significant.
Standardized difference of the means (absolute value); <0.1 considered to represent good balance.
Abbreviations: SLNB=sentinel lymph node biopsy, HN= Head and Neck, LM=lentigo maligna, NOS=Melanoma NOS, SS=superficial spreading