TABLE 2.

Sequence alignment of α-conotoxins targeting various nAChR subtypes

^a Amino acids homologous to RegIIA are labeled with a grey background. The conserved cysteine framework is highlighted in yellow. * indicates an amidated C terminus; ^ free carboxyl C terminus; and ^# presence of additional subunits.

^b Peptides inhibiting the α3β4 nAChR subtype and their corresponding IC₅₀ values are shown.