Effects of miR-193a-3p and ERBB4 on the growth of lung cancer cell xenografts in mice.
A, body weights of mice implanted with A549-Luc, A549-Luc-miR-193a-3p, or A549-Luc-ERBB4 were performed at 0, 3, 10, 14, 17, 21, 24, 29, and 32 days. B, the tumor weight of mice implanted with A549-Luc, A549-Luc-miR-193a-3p, or A549-Luc-ERBB4 mice. C, quantitative RT-PCR analysis of miR-193a-3p levels in tumors from mice implanted with A549-Luc, A549-Luc-miR-193a-3p, or A549-Luc-ERBB4. D, quantitative RT-PCR analysis of ERBB4 mRNA levels in tumors from mice implanted with A549-Luc, A549-Luc-miR-193a-3p, or A549-Luc-ERBB4. E and F, Western blotting analysis of ERBB4 protein levels in tumors from mice implanted with A549-Luc, A549-Luc-miR-193a-3p, or A549-Luc-ERBB4. E, representative image; F, quantitative analysis. **, p < 0.01; ***, p < 0.001. Error bars, S.E.