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. 2014 Nov 19;290(2):960–971. doi: 10.1074/jbc.M114.591057

FIGURE 10.

FIGURE 10.

SRC inhibition with PP2 improves endothelial barrier function in Bmrp2+/− PECs. A, TEER. TEER was evaluated 30 min after treatment with 30 μm PP2. B and C, Transwell permeability for rhodamine-70-kDa dextran (70kD-Rhod) (B) and FITC-albumin (C). Cells were treated with 30 μm PP2 for 30 min before adding fluorophore-conjugated solutes. Studies were performed in wild-type (W1) and Bmpr2+/− PECs (N6) in triplicate. Results are expressed as the mean. Error bars represent S.E. *, p < 0.05; **, p < 0.01; ***, p < 0.001 versus untreated Bmpr2+/− PECs (t test).