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. 2014 Nov 19;290(2):960–971. doi: 10.1074/jbc.M114.591057

FIGURE 9.

FIGURE 9.

Impaired endothelial barrier function in Bmrp2+/− PECs. A, TEER in three wild-type and three Bmpr2+/− PEC lines. B and C, transwell permeability assays for FITC-albumin (B) and rhodamine-70-kDa dextran (70kD-Rhod). (C). Studies were performed in triplicate in three wild-type lines and three Bmpr2+/− lines. D, comparison of permeability to rhodamine-70-kDa dextran at 37 and 4 °C. Transwell permeability assays were performed in wild-type (W1) and Bmpr2+/− (N6) PECs with six replicates/genotype/condition. All results are expressed as the mean. Error bars represent S.E. *, p < 0.01; **, p < 0.001 versus wild-type controls (t test).