Fig. 3.

A VcPbT neuron responsive to noxious mechanical and thermal stimuli but unresponsive to pruritic stimuli. A: bilateral lesions (arrows) made at LTPs in both the ipsilateral and contralateral Kölliker-Fuse nucleus. B: lesion (arrow) in the deep dorsal horn. C: receptive field. D: mechanical characterization. E: effects of thermal stimuli. F–L: the neuron was unresponsive to intradermal injections of vehicle, β-alanine, 5-HT, histamine, chloroquine, capsaicin, and mustard oil. Agents were injected in the same order as illustrated.