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. Author manuscript; available in PMC: 2015 Jan 14.
Published in final edited form as: Fungal Genet Biol. 2013 Apr 19;60:64–73. doi: 10.1016/j.fgb.2013.04.005

Fig. 2.

Fig. 2

Influence of WGA on pathophysiologic aspects of mice infected with C. neoformans. (A) Histology of lungs 5 days after intratracheal infection with C. neoformans. Similar pulmonary histologic profiles of mice receiving PBS, C. neoformans and WGA-treated cryptococci are shown. Some of the fungal cells identified in the images are highlighted with arrows. Images are representative of similar sections from mice in each group (n = 10). Original magnification 100×. (B) Treatment of lethally infected mice with WGA did not influence the course of animal cryptococcosis. Mice given PBS or WGA had similar mortality rates (n = 10, P = 0.7124). (C) Incubation of the lectin in the presence of PBS (control), trypsin or serum did not result in loss of its ability to recognize C. neoformans, as concluded by the similar profiles of fluorescence staining in all systems. The patterns of lectin staining in all cases corresponded to those described in previous studies (Fonseca et al., 2009; Rodrigues et al., 2008).